Sociopath John Cleaver calls a demon on the phone and challenges him to a fight to the death, only to be relentlessly stalked by a supernatural entity who always has the upper hand.

John and Brooke are on their own, hitchhiking from town to town as they hunt the last of the Withered through the Midwest - but the Withered are hunting them back, and the FBI is close behind. With each new town, each new truck stop, each new highway, they get closer to a vicious killer who defies every principle of profiling and prediction John knows how to use. Meanwhile, Brooke's fractured psyche flips in and out of lucidity, manifesting new names...